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March 2021 Viewpointe, Page 9
New Study Finds Linkage Between Childhood Diet
And The Health Of Your Micro Biome In Adulthood
By Tina Fernandez against pathogens (Gut Microbiome - an Overview | - Group #1: Fed standard diet, no access to the running
ScienceDirect Topics, n.d.) wheels.
“You are not only what you eat, but what you ate as In thinking about what factors in our everyday lives - Group #2: Western diet, no access to the running wheels.
a child!” impact our microbiome, the main two of relevance are diet - Group #3: Fed Standard diet, access to the running
A new study by the University of California Riverside and exercise. Interestingly, gut bacteria can be altered in wheels.
suggests that childhood eating habits may have a long- as little as twenty-four hours, with some studies showing - Group #4: Fed Western diet, access to the wheels.
term impact on the health of your gut as an adult. how a period of consumption high in fat & sugar leads The results of this experiment indicate that diet,
The microbiome has emerged as a strong topic of to a reduction in bacterial species in your gut (David exercise, and (in this case) linetype affect running and
interest for many scientists recently. Since animals and et al., 2014). A high-fat diet has been shown to cause a food consumption patterns, which in turn impact the gut
bacteria have coevolved over time, they have forged higher rate of amino acid metabolism and enzymes in the microbiome. The mice involved in the experiment were
complex relationships between host and symbiont. oxidative stress response, which is most likely a reaction observed for 6 weeks, then given a 25-day washout period
Our gastrointestinal tract is inhabited by a plethora of to the lack of proper nutrients within the gut as a result (about ~6 human years) in order to reevaluate their gut
different bacteria. To put things into perspective, the of these dietary habits (McNamara et al., 2021). microbiomes and determine if the juvenile eating habits had
gut microbiome expresses 3.3 million prokaryotic genes The purpose of this study, led by UCR evolutionary a long-term impact on microbiome health after aging.
(corresponding to the diverse bacteria), while the human physiologist Theodore Garland, was to evaluate the While the results to this experiment are credible, a lot
body expresses only 20,000 eukaryotic genes (NIH, long-term impact a Western diet (high fat and sugar) still remains elusive. The takeaway, as Garland says, is that
2012). The human gut microbiome is composed of four and exercise would have on the adult microbiome of “You are not only what you eat, but what you ate as a child!”
main phyla (groups or categories) of bacteria: Firmicutes, mice (the test subjects). Because mice are biologically
Bacteriodetes, Actinobacteria, and Proteobacteria (Gut very similar to humans, they are good models to use. Belizário, J. E., & Napolitano, M. (2015). Human
Microbiome - an Overview | ScienceDirect Topics, n.d.). The study used a total of 165 male mice in their juvenile microbiomes and their roles in dysbiosis, common diseases,
The bacteria have a variety of functions; they break down age period coming from two different lines. First, the and novel therapeutic approaches. Frontiers in Microbiology,
nutrients from the food we eat, regulate metabolism, and High Runner (HR) lines, which were selectively bred 6, 1050. https://doi.org/10.3389/fmicb.2015.01050
provide enhanced immunity through a variety of complex for high voluntary wheel-running behavior (more likely David, L. A., Maurice, C. F., Carmody, R. N.,
mechanisms. In addition, many of the fermentation to exercise voluntarily), and then the four control (C) Gootenberg, D. B., Button, J. E., Wolfe, B. E., Ling, A. V.,
byproducts such as acetate, propionate, and butyrate in lines. From the HR mice, four sub-groups were created Devlin, A. S., Varma, Y., Fischbach, M. A., Biddinger, S.
the GIT provide energy for epithelial cells and protection and evaluated: B., Dutton, R. J., & Turnbaugh, P. J. (2014). Diet rapidly
and reproducibly alters the human gut microbiome. Nature,
505(7484), 559–563. https://doi.org/10.1038/nature12820
Gut Microbiome—An overview | ScienceDirect Topics.
Boca Pointe Community Association, Inc. (n.d.). Retrieved February 24, 2021, from https://www.
sciencedirect.com/topics/medicine-and-dentistry/gut-
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The views of the writers of the various articles in this newspaper do not February 3). Childhood diet has lifelong impact:
Viewpointe of Boca Pointe is the newspaper necessarily reflect the views of the Boca Pointe Community Association. Effects of unhealthy food followed young mice into
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