Page 14 - Abacoa Community News - June '22

Page 14, Abacoa

FAU Features from page 10 FAU High School – Jupiter formats. An awards presentation portion of the symposium
followed, recognizing the 23 exceptional students and
sex-specific risk factors when examining differences in AD risk, Campus In Partnership their accomplishments which include: four peer-reviewed
but none have explored if these interventions result in differences research papers published; awards of more than $10,000 in
in real-world clinical practice. With Max Planck Academy grant funding and research awards to support their research
The study is an analysis of the Comparative Effectiveness Celebrates Inaugural endeavors; and numerous research presentations given at
Dementia & Alzheimer’s Registry (CEDAR) trial launched at university, state and national conferences.
Weill Medicine in 2015 and spearheaded by Isaacson, which Graduating Class FAU President John Kelly and David Fitzpatrick, Ph.D.,
has already demonstrated that individualized, multi-domain chief scientific director and CEO of MPFI, welcomed guests
interventions improved cognition and reduced the risk of AD in By Bethany Alex and kicked off the event recognizing the exceptional FAU
both women and men. Florida Atlantic University High School – Jupiter Campus High students and their mentors.
In the sub-group analysis, researchers evaluated the in partnership with Max Planck Academy recently celebrated “Congratulations to our first graduates of FAU High School
differential effectiveness of the clinical approach itself when the inaugural cohort of students’ extraordinary academic – Jupiter Campus in partnership with Max Planck Academy,
considering sex in higher-compliance participants (n=80) from performance and research projects at the Senior Research who were selected from a pool of top-tier candidates to
the original study cohort (n=154). Within this cohort, similar Symposium event hosted at the Max Planck Florida Institute of participate in this unique educational program,” said Kelly. “I
to the original study, participants were categorized by baseline Neuroscience (MPFI). am very proud of their many achievements and I look forward
diagnoses: normal cognition, subjective cognitive decline, and During the event, FAU High seniors presented their to hearing about their future successes.”
preclinical AD participants were classified as “Prevention.” Mild research and scholarly findings in both oral and poster FAU High School – Jupiter Campus in Partnership with
cognitive impairment due to AD and mild AD were classified as Max Planck Academy welcomed the first cohort
“Early Treatment.” of students in fall 2020, and is a premier, research-
Results of the study, published in the Journal of the focused institute that provides an early university
Prevention of Alzheimer’s Disease, showed that risk reduction entrance high school experience for STEM-
care in an Alzheimer’s Prevention Clinic setting led to focused juniors and seniors in high school. This
improvements in cognition in both women and men without unique partnership between FAU, MPFI and the
sex-differences. However, in the Prevention group, women Germany-based Max Planck Society, expanded
demonstrated greater improvements in the Multi-Ethnic Study on similar opportunities for FAU’s graduate
of Atherosclerosis risk score (MESA) than men. Women in the and undergraduate students. This extraordinary
Early Treatment group also demonstrated greater improvements program provides FAU High students access to the
in CV Risk Factors, Aging and Incidence of Dementia (CAIDE) laboratories of MPFI, allowing them to participate
risk score and the MESA-RS. The CAIDE is a validated risk in unparalleled education and world-class research
index that calculates late-life dementia risk based on midlife opportunities as part of their curriculum.
vascular risk factors such as body mass index, blood pressure,
cholesterol and smoking status, while the MESA estimates one’s FAU Features on page 15
risk of cardiovascular disease incidence over the next 10 years
using traditional risk factors.
is equally effective at improving cognitive function in both Experience Dentistry with a Woman’s Touch
“While care in an Alzheimer’s Prevention Clinic setting

women and men, our personally-tailored interventions led
to greater improvements in women compared to men across
Alzheimer’s and cardiovascular disease risk scales, as well as Cosmetic & Comprehensive Restorative Dentistry
blood biomarkers of risk such as blood sugar, LDL cholesterol,
and the diabetes test HbA1C,” said Isaacson, lead author and State of the Art & Same Day Restorations
director of the newly launched FAU Center for Brain Health
and the Alzheimer’s Prevention Clinic within the Schmidt Nitrous Oxide/Oxygen Sedation Available
College of Medicine, who conducted the study while at Weill
Cornell Medicine and NewYork-Presbyterian. “Our findings
are important because women are disproportionately affected Joanne Green, D.D.S.
by Alzheimer’s disease and population-attributable risk models
suggest that managing risk factors can prevent up to one-third 10887 N. Military Trail, Suite 6
of dementia cases, highlighting the immense potential that lies Palm Beach Gardens, FL 33410
in addressing modifiable risk factors.”
After undergoing baseline clinical assessments, which (561) 622-2815 • www.joannegreendds.com
included a detailed clinical history, physical examination,
anthropometrics, blood biomarkers, apolipoprotein-ε4 Medical College of Virginia School of Dentistry - Cum Laude
(APOE-e4) genotyping, and cognitive assessment, patients in the Hospital of the University of Penn - General Practice Residency Training
CEDAR study were given individually-tailored, multi-domain Harvard Dental School - Former Instructor
intervention recommendations informed by these clinical and Boston Brigham and Women’s Dental Group - Staff Dentist
biomarker data. Recommendation categories included patient
education/genetic counseling, individualized pharmacological
approaches (medications/vitamins/supplements), non-
pharmacological approaches (exercise counseling, dietary
counseling, vascular risk reduction, sleep hygiene, cognitive Need More Storage?
engagement, stress reduction, and general medical care) and
other evidence-based interventions.
“Our latest results suggest that the individualized management WE CAN HELP!
approach used by the CEDAR study in a real-world clinic may
offer equal cognitive benefits to both women and men, as well
as better mitigation of calculated Alzheimer’s disease and
cardiovascular disease risk in women compared to men,” said
Isaacson. “Our work also highlights the need for larger studies
focusing on sex differences in AD-related cognitive trajectories,
as the existing body of knowledge lacks conclusive evidence on NEW state of the art facility in Jupiter!
this issue.”
Isaacson and collaborators are planning on larger cohorts to
further define sex differences in AD risk reduction in clinical *
practice and hope to launch a multi-site international study soon FIRST
to draw more definitive conclusions. MONTHFREE!
Collaborators of the study include FAU’s Schmidt College
of Medicine; Cleveland Clinic; Lou Ruvo Center for Brain
Health, Las Vegas; Jersey Memory Assessment Service, Jersey,
United Kingdom; Alzheimer’s Prevention Clinic & Research * Certain restrictions apply. Mention or present this offer.
Center of Puerto Rico, San Juan; Weill Cornell Medicine and
NewYork-Presbyterian; New York; Norton Neuroscience Modern Security Climate-Controlled Secure Car
Institute, Louisville; McGill University Faculty of Medicine,
Montreal, Canada; University of New South Wales/University and Safety Storage Units Storage
of Notre Dame, Sydney, Australia; and Atria Institute, New York.
The study was primarily supported by the Women’s
Alzheimer’s Movement with additional support from the
Altman Family Fund, Zuckerman Family Foundation Ace’s Store. Pack. Move. 50 Frederick Small Road
for Alzheimer’s, the Harry T. Mangurian, Jr. Foundation,
philanthropic support from the patients of the Alzheimer’s And More! Jupiter, FL 33458
Prevention Clinic at Weill Cornell Medicine, the National
Institutes of Health (NIH), and the National Center for CompassSelfStorage.com (561) 556-2191
Advancing Translational Research (UL1TR002384) and NIH
(PO1AG026572).